PLP1 Monoclonal Antibody

Catalogue Numbers: MB67035-50, MB67035-100

Sizes: 50µl, 100µl

Product: Mouse IgM. Liquid in PBS, pH 7.3, 30% glycerol, and 0.01% sodium azide.

Swiss-Prot: P60201

Host: Mouse

Reactivity: Human

Applications: WB

All Applications: WB (1/500 - 1/1000)

Background: Myelin proteolipid protein (PLP1) corresponds to the majority of myelin proteins in the CNS, providing support to axons and modulating the axonal growth . DM20 is the result of the alternative splicing of the plp1 gene, which is linked to oligodendrocyte differentiation and survival. The imbalance of PLP1/DM20 is linked to Pelizaeus-Merzbacher disease , including mitochondrial damage . In addition, PLP1, but not DM20, can enter the mitochondria and participate in the metabolism of cells .

Purification and Purity: This antibody is purified through a protein G column.

Storage and Stability: Store at 4°C short term. Aliquot and store at -20°C long term. Avoid freeze-thaw cycles.

Specificity: Recognizes endogenous levels of PLP1 protein.

Extra Notes: Western blot analysis of PLP1 expression in C6 (A), Hela (B), mouse cerebellum (C) whole cell lysates.

Bioworld Molecular Weight: ~ 34 kDa

Note: For research use only, not for use in diagnostic procedure.

Alternative Name: PLP; Myelin proteolipid protein; PLP; Lipophilin

Immunogen: KLH-conjugated synthetic peptide encompassing a sequence within the center region of human PLP1. The exact sequence is proprietary.

Conjugate: Unconjugated

Modification: Unmodified