Monazomycin is a polyene-like antibiotic produced by Streptomyces. Monazomycin molecular weight is about 1200.

Product information

CAS Number: 11006-31-8

Molecular Weight: 1364.82

Formula: C72H133NO22

Chemical Name: 48-(8-aminooctan-2-yl)-8,10,16,20,24,26,28,32,36,38,40,42,44,46-tetradecahydroxy-9,15,17,19,21,25,31,33,39,41,47-undecamethyl-23-{[3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]oxy}-1-oxacyclooctatetraconta-13,17,21,29-tetraen-2-one

Smiles: CC1CCC(O)CC(O)C(C)C(O)C(C)C(O)CC(O)CC(O)C(C)C(OC(=O)CCCCCC(O)C(C)C(O)CCC=CC(C)C(O)C(C)=CC(C)C(O)C(C)=CC(OC2OC(CO)C(O)C(O)C2O)C(O)C(C)C(O)CC(O)C=CC(C)C1O)C(C)CCCCCCN

InChiKey: BTUZNIQVZBANAX-OIXFTHSFSA-N

InChi: InChI=1S/C72H133NO22/c1-39-22-19-20-25-55(79)46(8)54(78)24-17-15-18-26-62(84)95-71(42(4)23-16-13-14-21-31-73)50(12)59(83)37-53(77)36-58(82)48(10)66(88)47(9)56(80)34-51(75)29-27-40(2)63(85)41(3)28-30-52(76)35-57(81)49(11)67(89)60(33-45(7)65(87)44(6)32-43(5)64(39)86)93-72-70(92)69(91)68(90)61(38-74)94-72/h19,22,28,30,32-33,39-42,44,46-61,63-72,74-83,85-92H,13-18,20-21,23-27,29,31,34-38,73H2,1-12H3/b22-19-,30-28-,43-32-,45-33-

Technical Data

Appearance: Solid Power

Purity: ≥98% (or refer to the Certificate of Analysis)

Shipping Condition: Shipped under ambient temperature as non-hazardous chemical or refer to Certificate of Analysis

Storage Condition: Dry, dark and -20 ^oC for 1 year or refer to the Certificate of Analysis.

Shelf Life: ≥12 months if stored properly.

Stock Solution Storage: 0 - 4 ^oC for 1 month or refer to the Certificate of Analysis.

Drug Formulation: To be determined

HS Tariff Code: 382200

How to use

In Vitro:

Monazomycin is an antibiotic produced by Streptomyces. Its molecular weight is about 1200, and is related to that of polyene antibiotics. Monazomycin has an amino group that gives a positive charge to the molecule at neutral pH. When monazomycin is added in micromolar amounts to one side of a bilayer, membrane conductance becomes strongly voltage-dependent. Monazomycin is present in the solution in the form of relatively hydrophilic clusters and is adsorbed as such on top of the lipid bilayer, penetration into the bilayer following a potential jump is assumed to be preceded by a potential-independent disaggregation of the adsorbed clusters into adsorbed monomers.

Products are for research use only. Not for human use.